Dr. Horton gave this message from 2 Timothy 1:9-18 titled, "Saved Us to a Holy Calling" at The Gospel Coalition's 2018 West Coast Conference in Orange County, CA.
2 Timothy 1:9-18 (ESV)
Who saved us and called us to a holy calling, not because of our works but because of his own purpose and grace, which he gave us in Christ Jesus before the ages began, and which now has been manifested through the appearing of our Savior Christ Jesus, who abolished death and brought life and immortality to light through the gospel, for which I was appointed a preacher and apostle and teacher, which is why I suffer as I do. But I am not ashamed, for I know whom I have believed, and I am convinced that he is able to guard until that day what has been entrusted to me. Follow the pattern of the sound words that you have heard from me, in the faith and love that are in Christ Jesus. By the Holy Spirit who dwells within us, guard the good deposit entrusted to you.
You are aware that all who are in Asia turned away from me, among whom are Phygelus and Hermogenes. May the Lord grant mercy to the household of Onesiphorus, for he often refreshed me and was not ashamed of my chains, but when he arrived in Rome he searched for me earnestly and found me—may the Lord grant him to find mercy from the Lord on that day!—and you well know all the service he rendered at Ephesus.
Dr. Horton teaches on the basis of suffering witness, the example of suffering witness and the call to suffering witness. May these words encourage you to be a faithful witness in all the places our Lord calls you.
"This passage is a comfort to our brothers and sisters who are suffering for the Lord in areas of the world that are still hostile to the Gospel."